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. 2012 Jan 20;8:7–14. doi: 10.2147/TCRM.S22605

Table 2.

Nonepilepsy uses of RTG and other AEDs: CBZ, GBP, LTG, OXC, and TPM

AEDs* Nonepilepsy indications

Neuropathic pain Bipolar disorder Dystonia Cocaine addiction Alzheimer’s disease
RTG +a +a +a +a +a,b
CBZ +/− + +c +/− +
GBP + +/− +/− +/− +d
LTG + + a +/− +d
OXC + +/− + +
TPM +/− +/− + +/− +

Notes: +, drug effective; +/−, controversial data; −, drug ineffective;

a

experimental data;

b

initial clinical data;

c

dystonia as a result of drug toxicity;

d

limited number of patients.

*

All data are from references,39,6279 except for RTG, which are from references.4043,4547

Abbreviations: AED, antiepileptic drug; CBZ, carbamazepine; GBP, gabapentin; LTG, lamotrigine; OXC, oxcarbazepine; RTG, retigabine; TPM, topiramate.