Table 2.
The odds ratios (ORs) of rs12425791 and rs11833579 genotypes for ischemic stroke
| SNP | Total ischemic stroke | LAA | ||||||
|---|---|---|---|---|---|---|---|---|
| OR* | 95% CI | P-value | q-value† | OR* | 95% CI | P-value | q-value† | |
| rs12425791 | ||||||||
| Additive | 1.00 | (0.84-1.19) | 0.977 | 0.977 | 1.03 | (0.79-1.34) | 0.831 | 0.997 |
| Dominant | 0.90 | (0.72-1.11) | 0.304 | 0.609 | 0.87 | (0.63-1.19) | 0.384 | 0.610 |
| Recessive | 1.67 | (1.05-2.66) | 0.031 | 0.183 | 2.30 | (1.22-4.34) | 0.010 | 0.062 |
| rs11833579 | ||||||||
| Additive | 1.01 | (0.87-1.18) | 0.860 | 0.977 | 1.00 | (0.79-1.26) | 0.999 | 0.999 |
| Dominant | 0.95 | (0.77-1.17) | 0.596 | 0.893 | 0.88 | (0.64-1.20) | 0.407 | 0.610 |
| Recessive | 1.21 | (0.88-1.67) | 0.241 | 0.609 | 1.35 | (0.85-2.14) | 0.200 | 0.599 |
*: adjustment for age, gender, hypertension, diabetes mellitus, heart disease, dyslipidemia, cigarette smoking or alcohol drinking, and obesity
†: False discovery rate (FDR) was controlled using the Benjamini-Hochberg procedure
LAA, large artery atherosclerosis