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. 2011 Dec 20;11:49. doi: 10.1186/1472-6807-11-49

Figure 8.

Figure 8

Previously determined biological functions associated with the N- and C-terminal binding domains of Vpr to CypA. Linear structure of full length Vpr with incorporated biological functions connected to the determined N- and C-terminal binding regions of Vpr to CypA including G2 cell cycle arrest [30-34,36,71], nuclear localization of the protein [30,31,68-70], ANT/apoptosis [55-63], and replication of R5 tropic HIV-1 [38,67]. Residues belonging to the N- and C-terminal binding regions of Vpr to CypA are labeled in blue.