Table 1. Patient characteristics.
CD | UC | HC | ||
Discovery Set | N | 102 | 102 | 102 |
Age, years | 36.1±9.9 | 35.9±9.4 | 36.4±8.6 | |
Female, n (%) | 32 (31) | 32 (31) | 32 (31) | |
Mean disease duration, years | 11.0±7.4 | 7.8±6.7 | – | |
Mean age at diagnosis, years | 25.1±7.7 | 28.1±8.5 | – | |
Active disease | 29 | 38 | – | |
CD characteristics | ||||
Disease location | ||||
Small bowel | 31 | – | – | |
Colon | 9 | – | – | |
Both | 59 | – | – | |
Others | 3 | – | – | |
Behavior (Montreal classification) | ||||
B1: non-stricturing, non-penetrating | 26 | – | – | |
B2: stricturing | 42 | – | – | |
B3: penetrating | 34 | – | – | |
p: perianal disease modifier | 40 | – | – | |
UC characteristics | ||||
Disease location | ||||
Proctitis | – | 12 | – | |
Left sided colitis | – | 43 | – | |
Entire colitis | – | 47 | – | |
Treatment | ||||
Enteral nutrition | 44 | 1 | – | |
Steroids | 12 | 37 | – | |
Salicylates | 91 | 98 | – | |
Immunosuppressors | 56 | 25 | – | |
Infliximab | 14 | 0 | – | |
Biomarker levels | Median (interquartile range) | |||
Albumin (mg/dl) | 4.2 (3.8–4.4) | 4.5 (4.1–4.6) | 4.6 (4.4–4.8) | |
C-reactive Protein (mg/dl) | 0.22 (0.03–0.77) | 0.19 (0.03–0.25) | 0.02 (0.01–0.04) | |
Hemoglobin (g/dl) | 12.8 (11.5–13.9) | 13.9 (13.3–14.8) | 15.2 (13.6–15.7) | |
Validation Set | n | 63 | 120 | 108 |
Age, years | 32.3±11.2 | 42.6±16.2 | 42.4±7.9 | |
Female, n (%) | 20 (33) | 40 (33) | 34 (32) |
Plus-minus values are means±standard deviation.