Table 2.
Tumor Passage No. | Number of mice injected | Number mice with tumor | Take-rate |
---|---|---|---|
P0 | |||
SC | 10 | 10 | 100% |
IF | 8 | 8 | 100% |
P1 | |||
SC | 18 | 18 | 100% |
IF | 29 | 19 | 66% |
P2 | |||
SC | 10 | 10 | 100% |
IF | 23 | 14 | 67% |
Tumor passage number: P0 = primagraft: primary patient sample injected; P1 = first serial passage of tumor cells, that is, tumor cells harvested from P0 tumors are re-implanted into new mice and tumors allowed to develop; P2 = second serial passage of xenograft tumors; SC = sub-cutaneously transplanted tumors; IF = intra-femorally transplanted tumors.