Table 2.

Enriched networks at different time points of MDV infection in different chicken lines

Lines	Time points	Score	Focus Molecules	Top Functions
L63	5dpi	46	29	Digestive System Development and Function, Hepatic System Development and Function, Organ Development
		36	25	Skeletal and Muscular System Development and Function, Tissue Morphology, Lipid Metabolism
		35	25	Amino Acid Metabolism, Small Molecule Biochemistry, Cellular Compromise
		28	21	Carbohydrate Metabolism, Lipid Metabolism, Small Molecule Biochemistry
		24	20	Drug Metabolism, Endocrine System Development and Function, Lipid Metabolism
	10dpi	36	25	Lipid Metabolism, Small Molecule Biochemistry, Vitamin and Mineral Metabolism
		30	21	Infection Mechanism, Visual System Development and Function, Dermatological Diseases and Conditions
		30	21	Molecular Transport, Cellular Movement, Cell Cycle
		27	22	Neurological Disease, Carbohydrate Metabolism, Lipid Metabolism
		26	19	Organismal Injury and Abnormalities, Infection Mechanism, Infectious Disease
	21dpi	39	28	Cell Morphology, Cellular Function and Maintenance, Cell Death
		34	22	Cardiovascular System Development and Function, Organismal Development, Tissue Development
		27	19	Carbohydrate Metabolism, Small Molecule Biochemistry, Cellular Assembly and Organization
		24	17	Cell-To-Cell Signaling and Interaction, Cell-mediated Immune Response, Cellular Development
		22	16	Lipid Metabolism, Small Molecule Biochemistry, Behavior
L72	10dpi	29	21	Cardiac Arrythmia, Cardiovascular Disease, Genetic Disorder
		27	22	Cellular Assembly and Organization, Cellular Compromise, Free Radical Scavenging
		26	19	Cell-To-Cell Signaling and Interaction, Cellular Growth and Proliferation, Skeletal and Muscular System Development and Function
		24	18	Cell Morphology, Connective Tissue Development and Function, Skeletal and Muscular System Development and Function
		22	17	Infection Mechanism, Cardiovascular System Development and Function, Organismal Development
	21dpi	38	27	Cell Morphology, Connective Tissue Development and Function, Skeletal and Muscular System Development and Function
		32	24	Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry
		31	24	Embryonic Development, Tissue Development, Cell Cycle
		31	24	Cell Morphology, Skeletal and Muscular System Development and Function, Connective Tissue Development and Function
		23	20	Connective Tissue Disorders, Genetic Disorder, Cellular Assembly and Organization
RCS- M	5dpi	32	22	Cell Morphology, Cellular Development, Cell Death
		32	22	Cellular Assembly and Organization, Cell Morphology, Cellular Development
		30	21	Cell Morphology, Cellular Development, Skeletal and Muscular System
				Development and Function
		28	20	Amino Acid Metabolism, Small Molecule Biochemistry, Drug Metabolism
		24	18	Inflammatory Disease, Renal and Urological Disease, Amino Acid Metabolism
	10dpi	34	23	Carbohydrate Metabolism, Lipid Metabolism, Small Molecule Biochemistry
		31	21	Antigen Presentation, Cell-To-Cell Signaling and Interaction, Cellular Function and Maintenance
		29	20	Molecular Transport, Drug Metabolism, Lipid Metabolism
		21	16	Carbohydrate Metabolism, Drug Metabolism, Small Molecule Biochemistry
		20	16	Dermatological Diseases and Conditions, Genetic Disorder, Immunological Disease
	21dpi	33	23	Cell Morphology, Cellular Assembly and Organization, Cell-To-Cell Signaling and Interaction
		26	19	Connective Tissue Development and Function, Skeletal and Muscular System Development and Function, Tissue Morphology
		24	18	Carbohydrate Metabolism, Small Molecule Biochemistry, Organismal Functions
		24	23	Cell Death, Gene Expression, Cellular Function and Maintenance
		23	18	Lipid Metabolism, Molecular Transport, Small Molecule Biochemistry

*The genes input in IPA software were obtained using P < 0.05, |LogFC|>1.5 and FDR<0.5.