Table 1.
Patient characteristics and pregnancy outcomes
| Mother | Neonate | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Age (years) | PPW (kg) | DD (mg) | DDD (mg) | TF | Indication | Compliance* | Complications | Sex | GA | BW (g) | Breast feeding |
| 1 | 36 | 90 | 37.5 | 37.5 | IR | PD | 110% | – | M | 37 + 5 | 3520 | No |
| 2 | 41 | 84 | 75 | 75 | SR | MDD | 97% | – | F | 37 + 5 | 2560 | Yes |
| 3 | 36 | 64 | 75 | 113 | SR | PD | 101% | Caesarean section due to presence of amniotic fluid containing meconium, diabetes gravidarum, pregnancy-related hypertension | M | 38 + 4 | 2890 | No |
| 4 | 40 | 81 | 75 | 100 | SR | PD | 100% | Pre-eclampsia; caesarean section due to delayed delivery | F | 38 + 1 | 4020 | No |
| 5 | 32 | 80 | 60 | 60 | IR | MDD | 96% | Caesarean section due to delayed delivery | M | 37 + 1 | 2700 | No |
| 6 | 30 | 63 | 50 | 50 | IR | MDD | 96% | Diabetes, not pregnancy related | F | 38 + 1 | 3230 | Yes |
| 7 | 34 | 60 | 100 | 125 | IR | OCD | 97% | Caesarean section due to unsuccessful vacuum extraction and delayed delivery | M | 39 + 3 | 3490 | Yes |
| 8 | 26 | 50 | 50 | 50 | IR | PD | 101% | Pre-eclampsia | F | 35 + 5 | 2515 | Yes |
| 9 | 26 | 50 | 50 | 50 | IR | PD | 101% | Pre-eclampsia | F | 34 + 2 | 2365 | Yes |
| 10 | 31 | 125 | 20 | 25 | IR | PD | 101% | – | F | 38 + 1 | 4300 | Yes |
| 11 | 29 | 52 | 125 | 125 | IR | OCD | 76% | – | M | 36 + 6 | 2740 | No |
Abbreviations:. BW, birth weight (in grams); DD, daily dose at time of inclusion (in milligrams); DDD, daily dose at delivery (in milligrams); F, female; GA, gestational age (weeks + number of days); IR, immediate release; M, male; MDD, major depressive disorder; OCD, obsessive compulsive disorder; PD, panic disorder; PPW, prepregnancy weight (in kilograms); SR, sustained release; and TF, tablet formulation.
*
Calculated with medication event monitoring system-recorded administration times.