Table 1.
KAP genes identified to date in human and sheep
Family | Category1 | Known family members2,3,4 | |
---|---|---|---|
Human | Sheep | ||
KAP1 | HS | 4 (2)a,b | 3 (3)i-l,5 |
KAP2 | HS | 5+1a | 06 |
KAP3 | HS | 3+1a | 2+1 (1)m,n |
KAP4 | UHS | 11+1 (10)a,c | 2o |
KAP5 | UHS | 12+2d | 3+1 (1)p,q |
KAP6 | HGT | 3e | 1 (1)r,s |
KAP7 | HGT | 1e | 1 (1)n,t,u |
KAP8 | HGT | 1+2e | 1 (1)t,u,v |
KAP9 | UHS | 7+1a | |
KAP10 | HS | 12+1f,g | |
KAP11 | HS | 1f | |
KAP12 | HS | 4+1f,g | |
KAP13 | HS | 4+2f | |
KAP15 | HS | 1f | |
KAP16 | HS | 1a | |
KAP17 | UHS | 1a | |
KAP19 | HGT | 7+4f | |
KAP20 | HGT | 2f | |
KAP21 | HGT | 2+1f | |
KAP22 | HGT | 1f | |
KAP23 | HS | 1h | |
KAP24 | HS | 1h | |
KAP25 | HS | 1h | |
KAP26 | HS | 1h | |
KAP27 | HS | 1h | |
Total | 88+17 (12) | 13+2 (9) |
1 HS: ≤30 mol % cysteine; UHS: >30 mol % cysteine; HGT: 35-60 mol % of glycine and tyrosine.
2 Membership is based on the identification of the gene, and not the protein.
3 Numbers after “+” represent pseudogenes, and numbers of family members having genetic variation reported are shown in the brackets.
4 Superscript letters indicate the references from which the genetic information was derived: a35, b7, c29, d40, e41, f42, g43, h30, i44, j3, k36, l4, m45, n37, o26, p25, q5, r23, s6, t46, u38 and v39.
5 While there are currently only three genes reported in the literature for KAP1, there are four known protein sequences.
6 No ovine genes have been identified, despite three protein sequences having been reported 10,47.