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. 2011 Dec 28;13(1):369–382. doi: 10.3390/ijms13010369

Figure 4.

Figure 4

Effect of VCR and PTX treatment on Akt kinase protein expression and specific phosphorylation. The sensitive L1210 and resistant L1210/VCR cells were treated with 100 μmol/L PTX and/or 1.2 μmol/L VCR for 24 h, Akt kinase protein expression and its specific fosforylation (on Ser 473) were determined by Western blot analysis using a specific antibodies. Blots of three independent experiments were quantified and obtained data were evaluated by Student’s t test. * Different from control (without drugs) at significance level p < 0.01.