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. 2011 May 3;76(18):1589–1595. doi: 10.1212/WNL.0b013e3182190f74

Figure. Flow chart of the diagnosis of neuromyelitis optica (NMO) in the study.

Figure

The figure shows the diagnostic process of the selected study population. The clinical data and the imaging data were prepared to establish the clinical NMO diagnosis without knowledge of the aquaporin-4 (AQP4) antibody serologic status. The AQP4 antibodies were measured without knowledge of the clinical status. As an endpoint, the final diagnosis of NMO was made. *Number of patients where the diagnosis depended on AQP4 antibody positivity. MS = multiple sclerosis; ON = optic neuritis; TM = transverse myelitis.