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. 2011 Nov 16;3(3):e26. doi: 10.4081/hr.2011.e26

Table 2. Comparing Bcl-2 expression and prognostic parameters in NHL group.

Parameter Bcl-2 positive Bcl-2 negative P Significance
N. cases % cases N. cases % cases
Age (mean) ≥45 yrs 12 75 16 57.1 0.236 NS
<45 yrs 4 25 12 42.9
Sex (mean) M 10 62.5 16 57.1 0.728 NS
F 6 37.5 12 42.9
Hb g/dL (mean) ≥10 8 50 14 50 1 NS
<10 8 50 14 50
Plt ×109/L (mean) ≥150 4 25 22 78.6 0.001 HS
<150 12 75 6 21.4
TLC ×109/L (mean) ≥8 8 50 6 21.4 0.052 NS
<8 8 50 22 78.6
LDH IU/L (mean) ≥500 14 87.5 12 42.9 0.004 HS
<500 2 12.5 16 57.1
Stage I 0 0 6 21.4 0.239 NS
II 2 12.5 4 14.3
III 6 37.5 8 28.6
IV 8 50 10 35.7
Pattern Diffuse 4 25 2 7.2 0.36 NS
Patchy 4 25 10 35.7
Interstitial 2 12.5 6 21.4
Mixed 6 37.5 10 35.7
Therapeutic Responders 2 12.5 18 64.3 0.001 HS
response Non-responders 14 87.5 10 35.7
Clinical Complete remission 2 12.5 22 78.6 0.001 HS
outcome Relapse 14 87.5 6 21.4
Fate Alive 7 43.8 24 85.7 0.003 HS
Death 9 56.2 4 14.3

S, significant; NS, non-significant; TLC, total leukocytic count; Hb, hemoglobin; Plts, platelets; BML, bone marrow lymphocytes; LDH, lactate dehydrogenase.