Table 2. Comparing Bcl-2 expression and prognostic parameters in NHL group.
Parameter | Bcl-2 positive | Bcl-2 negative | P | Significance | |||
---|---|---|---|---|---|---|---|
N. cases | % cases | N. cases | % cases | ||||
Age (mean) | ≥45 yrs | 12 | 75 | 16 | 57.1 | 0.236 | NS |
<45 yrs | 4 | 25 | 12 | 42.9 | |||
Sex (mean) | M | 10 | 62.5 | 16 | 57.1 | 0.728 | NS |
F | 6 | 37.5 | 12 | 42.9 | |||
Hb g/dL (mean) | ≥10 | 8 | 50 | 14 | 50 | 1 | NS |
<10 | 8 | 50 | 14 | 50 | |||
Plt ×109/L (mean) | ≥150 | 4 | 25 | 22 | 78.6 | 0.001 | HS |
<150 | 12 | 75 | 6 | 21.4 | |||
TLC ×109/L (mean) | ≥8 | 8 | 50 | 6 | 21.4 | 0.052 | NS |
<8 | 8 | 50 | 22 | 78.6 | |||
LDH IU/L (mean) | ≥500 | 14 | 87.5 | 12 | 42.9 | 0.004 | HS |
<500 | 2 | 12.5 | 16 | 57.1 | |||
Stage | I | 0 | 0 | 6 | 21.4 | 0.239 | NS |
II | 2 | 12.5 | 4 | 14.3 | |||
III | 6 | 37.5 | 8 | 28.6 | |||
IV | 8 | 50 | 10 | 35.7 | |||
Pattern | Diffuse | 4 | 25 | 2 | 7.2 | 0.36 | NS |
Patchy | 4 | 25 | 10 | 35.7 | |||
Interstitial | 2 | 12.5 | 6 | 21.4 | |||
Mixed | 6 | 37.5 | 10 | 35.7 | |||
Therapeutic | Responders | 2 | 12.5 | 18 | 64.3 | 0.001 | HS |
response | Non-responders | 14 | 87.5 | 10 | 35.7 | ||
Clinical | Complete remission | 2 | 12.5 | 22 | 78.6 | 0.001 | HS |
outcome | Relapse | 14 | 87.5 | 6 | 21.4 | ||
Fate | Alive | 7 | 43.8 | 24 | 85.7 | 0.003 | HS |
Death | 9 | 56.2 | 4 | 14.3 |
S, significant; NS, non-significant; TLC, total leukocytic count; Hb, hemoglobin; Plts, platelets; BML, bone marrow lymphocytes; LDH, lactate dehydrogenase.