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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Ann Surg Oncol. 2010 Aug 12;17(12):3370–3378. doi: 10.1245/s10434-010-1147-4

TABLE 2 Immunohistochemistry for mismatch repair (MMR) proteins

NCI 5-marker MSI+ (N = 96)
MSS (N = 261)(%)
3-Marker+ cases (N = 23) (%) 3-Marker− cases (N = 19) (%) P value
MLH1 deficient 52 0 .000* 0
MSH2 deficient 4 0 .012* 0
MSH6 deficient 4 0 .012* 0
PMS2 deficient 57 0 .000* 0
Any MMR protein deficient 71 0 .000* 0
*

P < .001, for comparisons to 3-marker− cases