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. 2012 Jan 19;8(1):e1002352. doi: 10.1371/journal.pcbi.1002352

Figure 1. Aerobic glycolysis in bloodstream form T. brucei.

Figure 1

Abbreviations: Metabolites: Glc-6-P = Glucose 6-phosphate, Fru-6-P = Fructose 6-phosphate, Fru-1,6-BP = Fructose 1,6-bisphosphate, DHAP = dihydroxyacetone phosphate, GA-3-P = glyceraldehyde 3-phosphate, Gly-3-P = glycerol 3-phosphate, 1,3-BPGA = 1,3-bisphosphoglycerate, 3-PGA = 3-phosphoglycerate, 2-PGA = 2-phosphoglycerate, PEP = phosphoenolpyruvate. Reactions: 1 = transport of glucose across the cytosolic membrane, 2 = transport of glucose across the glycosomal membrane, 3 = hexokinase, 4 = phosphoglucose isomerase, 5 = phosphofructokinase, 6 = aldolase, 7 = triosephosphate isomerase, 8 = glyceraldehyde 3-phosphate dehydrogenase, 9 = phosphoglycerate kinase, 10 = transport of 3-PGA across the glycosomal membrane, 11 = phosphoglycerate mutase, 12 = enolase, 13 = pyruvate kinase, 14 = transport of pyruvate across the cytosolic membrane, 15 = glycerol 3-phosphate dehydrogenase, 16 = glycerol kinase, 17 = DHAP-Gly-3-P antiporter, 18 = glycerol-3-phosphate oxidation, 19 = ATP utilisation, 20 = adenylate kinase.