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The NSAIDs that impair cell migration do not affect the total expression (panel A) of Kv1.6 by IEC-Cdx2; however, these drugs do diminish the cell surface expression (panel B) and increase the non-surface expression (panel C) of Kv1.6. Monolayer cultures were exposed to drug for 72 h before surface biotinylation and lysis. Drug concentrations were identical to those used in Figures 1–4. Asterisks indicate significant differences (p < 0.05).
