Table 3.
Relationship between nonspecific lesions of arteries/arterioles and TMA in normotensive and hypertensive patients (MHT excluded)
| Normotensive Patients | Hypertensive Patients | ||||||
|---|---|---|---|---|---|---|---|
| TMA Present | TMA Absent | P Value | TMA Present | TMA Absent | P Value | ||
| Number of patients | 20 | 43 | 30 | 13 | |||
| Lesion | |||||||
| arteriosclerosis (global) | 2.21 (2–3) | 1.14 (0–2) | 0.0004 | 2.57 (2–3) | 1.69 (1–2) | 0.003 | |
| arterial intimal sclerosis | 1.20 (0–2) | 0.54 (0–1) | 0.01 | 1.85 (1–2.5) | 0.71 (0–1) | 0.001 | |
| arterial S/M hypertrophy | 0.60 (0–1) | 0.39 (0–1) | >0.10 | 0.85 (0–2) | 0.20 (0.–0.25) | 0.02 | |
| arterial S/M hyalin deposits | 0.30 (0–1) | 0.15 (0–0) | >0.10 | 0.58 (0–1) | 0.08 (0–0) | 0.01 | |
| arteriolar lumen caliber | 2.25 (2–3) | 2.77 (3–3) | 0.0002 | 2.25 (2–3) | 2.76 (3–3) | 0.01 | |
| arteriolar S/M hypertrophy | 0.1 (0–0) | 0.01 (0–0) | >0.10 | 0.62 (0–1) | 0.23 (0–0) | 0.02 | |
| arteriolar hyalin deposits | 1.20 (0.5–2) | 0.51 (0–1) | 0.01 | 0.93 (0–2) | 1.31 (0–2) | >0.10 | |
MHT cases could not be broken down in this fashion because all patients had some form of TMA. Values expressed as mean (25th to 75th percentile). P values calculated by Mann–Whitney U test. S/M, smooth muscle.