Figure 2.

Serum sFlt1 levels are increased during acute PR3-associated vasculitis. (A) Serum sFlt1 levels (log scale) in 18 patients with PR3-associated vasculitis at the disease onset and at 3-month follow-up. ^†P=0.0026, paired t test. (B) Serum C5a levels in acute and remission ANCA-associated vasculitis samples and from healthy controls demonstrating significantly elevated levels in acute disease compared with disease remission and those found in healthy controls. CT, healthy controls. ^††P=0.001 for ANCA-associated vasculitis acute versus remission and controls.