TABLE 1.
THS + placebo | THS + rFXIII | TSS + placebo | TSS + rFXIII | |
---|---|---|---|---|
Before THS or TSS | ||||
MBP (mm Hg) | 96.7 ± 14.2 | 86.9 ± 9.2 | 87.9 ± 9.4 | 88.9 ± 7.5 |
SBP (mm Hg) | 122.4 ± 18.2 | 111.5 ± 13.2 | 108.0 ± 11.0 | 106.6 ± 12.2 |
HR (beat/min) | 319.2 ± 60.9 | 305.7 ± 47.1 | 313.6 ± 20.1 | 308.0 ± 24.9 |
At the end of resuscitation after the 90 min THS or TSS period | ||||
MBP (mm Hg) | 94.2 ± 21.1 | 91.5 ± 10.3 | 89.4 ± 6.2 | 90.3 ± 8.4 |
SBP (mm Hg) | 137.6 ± 13.3*** | 124.1 ± 14.0*** | 107.6 ± 8.3 | 108.0 ± 13.9 |
HR (beat/min) | 363.5 ± 54.1*** | 355.9 ± 42.5*** | 316.3 ± 26.5 | 310.5 ± 17.7 |
3 h after the end of resuscitation or TSS period | ||||
MBP (mm Hg) | 75.1 ± 8.8* | 91.7 ± 7.1 | 87.3 ± 9.7 | 93.0 ± 7.2 |
SBP (mm Hg) | 106.7 ± 8.3** | 111.5 ± 10.1 | 105.4 ± 8.2 | 112.0 ± 13.4 |
HR (beat/min) | 388.0 ± 37.2* | 346.0 ± 48.6 | 319.8 ± 28.2 | 317.8 ± 23.6 |
MBP = mean blood pressure; SBP = systolic blood pressure; HR = heart rate.
P < 0.05 versus before THS and versus all other groups after THS and resuscitation.
P < 0.05 versus after THS and resuscitation.
P < 0.05 versus both shams.