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. 2012 Feb 1;7(2):e30942. doi: 10.1371/journal.pone.0030942

Figure 3. Stathmin and GRPR are not involved in contextual fear extinction.

Figure 3

(A) Representation of the protocol used for acquisition (tone-shock explicitly unpaired, left) and extinction (right) of contextual fear conditioning. (B) Acquisition (left) and extinction (right) performances of GRPR WT and KO mice (12 WT and 12 KO). (C) Acquisition (left) and extinction (right) performances of stathmin WT and KO mice (11 WT and 11 KO). Acquisition performance is expressed as percentage of freezing minute by minute and extinction performance is expressed as percentage of freezing during 10 minutes of the session during 4 days of extinction. Results are presented as mean ± SEM. # represents significant difference between groups during the whole extinction phase.