Table 1. Amount of polyQs in eukaryotes.
Organism | Group | N entries | N polyQs | N polyQ proteins |
Human (Homo sapiens) | primate | 37 067 | 299 | 248 |
Chimpanzee (Pan troglodytes) | primate | 27 903 | 227 | 193 |
Orangutan (Pongo pygmaeus) | primate | 19 440 | 236 | 189 |
Mouse (Mus musculus) | rodent | 32 698 | 314 | 262 |
Dog (Canis familiaris) | mammal | 20 037 | 170 | 135 |
Xenopus (Xenopus tropicalis) | amphibian | 15 971 | 133 | 117 |
Chicken (Gallus gallus) | bird | 15 177 | 165 | 135 |
Zebrafish (Danio rerio) | fish | 17 275 | 191 | 159 |
Fruit fly (Drosophila melanogaster) | insect | 18 253 | 2 242 | 1 162 |
Worm (Caenorhabditis elegans) | nematode | 20 878 | 259 | 192 |
Fungus (Aspergillus niger) | ascomycota | 11 746 | 159 | 137 |
Yeast (Saccharomyces cerevisiae) | ascomycota | 6 416 | 187 | 141 |
Yeast (Schizosaccharomyces pombe) | ascomycota | 4 958 | 19 | 16 |
Amoeba (Dictyostelium discoideum) | protist | 5 856 | 1 792 | 1 005 |
Plasmodium (Plasmodium falciparum) | protist | 5 331 | 27 | 27 |
Rice (Oryza sativa) | angiosperm | 52 694 | 869 | 789 |
Thale cress (Arabidopsis thaliana) | angiosperm | 31 344 | 340 | 285 |
The search engine was applied to 17 eukaryotic proteomes in search for imperfect polyQ repeats. N entries refer to the total number of proteins present in the input proteome after isoforms removal (see Methods); N polyQs refer to the number of imperfect polyQ repeats retrieved by the program (see Methods and Figure 1 for definition of an imperfect polyQ repeat); N polyQ proteins refer to the number of polyQs-containing proteins.