Figure 1.
Association signals in and adjacent to the LPA gene region on chromosome 6q. Single-nucleotide polymorphisms include all single-nucleotide polymorphisms (161 genotyped and 343 imputed single-nucleotide polymorphisms) within the region from 160 620 to 161 120 kb. The vertical axis representing the –log10 P-values. Recombination rates in this region are plotted in the background in blue. A pair-wise linkage disequilibrium between rs10455872 and other single-nucleotide polymorphisms was estimated using HapMap LD data. Six single-nucleotide polymorphisms labelled were selected from the forward-selection regression model.