Table 2.

Outcomes from Periodontal Infection and Prematurity Study Randomized Controlled Trial

	Treatment
Outcome measure	Active	Control	p value	Relative risk (95% CI)
Gestational age: live births only	n=359	n=361
Average gestational age, weeks	38.6 (2.8)	38.8 (2.3)	0.47
Gestational age <35 weeks, %	8.6	5.5	0.11	1.56 (0.91–2.68)
Spontaneous preterm delivery, %	5.3	4.4	0.59	1.19 (0.62–2.28)
Indicated preterm delivery, %	3.3	1.1	0.05	3.01 (0.98–9.27)
Gestational age <37 weeks, %	16.2	13.0	0.24	1.24 (0.87–1.77)
Spontaneous preterm delivery, %	10.6	10.3	0.88	1.03 (0.67–1.59)
Indicated preterm delivery, %	5.6	2.8	0.06	2.01 (0.95–4.24)
Birth weight: live births only	n=357	n=359
Average birth weight, g	3076.1	3143.8	0.14
Birth weight <2500 g, %	13.5	9.8	0.12	1.38 (0.92–2.08)
Birth weight <1500 g, %	3.1	1.7	0.22	1.84 (0.69–4.93)
Adverse pregnancy/neonatal outcomes	n=376	n=380
Stillbirth, %	2.1	2.4	0.82	0.90 (0.35–2.30)
Miscarriage, %	4.0	3.2	0.54	1.26 (0.60–2.66)
Composite neonatal morbidity/mortality, %	10.6	8.2	0.24	1.30 (0.83–2.04)

Adapted from Macones et al.³