Fig. 6.

Inhibitor-resistant A*68:01 ligands predominantly arise from small and basic proteins. The molecular mass (log MW) of the parental proteins from inhibitor-sensitive and -resistant A*68:01 ligands was plotted versus their theoretical pI. The value of 30 kDa corresponds to the highest molecular mass (30267 Da) observed among parental proteins of inhibitor-resistant ligands derived from internal sequences. The two parental proteins of ligands matching N- or C-terminal sequences were not included.