Table III. Effect of inhibitors on the cleavage of synthetic peptide precursors by proteasome 20S.

Activity	No inhibitor		MG-132		Epoxomicin
31-mer	N. of Cleavages	% Contributiona	N. of Cleavages	% Contributiona	N. of Cleavages	% Contributiona
Tryptic	3	15.4	2	8.3	3	11.6
Chymotryptic	13	65.1	11	70.3	9	70.1
Caspase	2	1.2	2	0.9	0	0
Other	11	18.3	7	20.5	7	18.4
Total	29	100	23	100	20	100
30-mer	N. of Cleavages	% Contributionb	N. of Cleavages	% Contributionb	N. of Cleavages	% Contributionb
Tryptic	4	27.6	4	17.3	3	12.7
Chymotryptic	8	25.4	9	35.2	6	37.5
Caspase	3	21.1	2	12.1	2	12.5
Other	7	25.9	8	35.4	7	37.2
Total	22	100	23	100	18	100

^a Added values from Table VIS.

^b Added values from Table VIIS.