Table 2.
Regions reaching significance for the between-group analysis (OB vs. HWC) contrast between food and non-food categories.
| Condition | Contrast | Region of Interest | Hemisphere | Voxels | x | y | z1 | Z-score | Uncorrected p-value2 |
Voxel- level PFWE-corr3 |
|---|---|---|---|---|---|---|---|---|---|---|
| Pre-meal | OB > HWC | |||||||||
| Hypothalamus | L R |
19 19 |
−3 5 |
−9 −3 |
−3 −6 |
2.89 2.76 |
0.002 0.003 |
0.048 0.064 |
||
| Amygdala | L | 14 | −29 | −4 | −14 | 2.44 | 0.007 | 0.137 | ||
| OFC | L | 43 | −30 | 6 | −17 | 3.43 | 0.000 | 0.092 | ||
| mPFC | R | 18 | 2 | 54 | 9 | 3.18 | 0.001 | 0.062 | ||
| HWC > OB | ||||||||||
| none | ||||||||||
| Post-meal | OB > HWC | |||||||||
| Hypothalamus | R | 7 | 5 | −9 | −6 | 2.61 | 0.004 | 0.080 | ||
| DLPFC | L | 30 | −44 | 37 | 21 | 2.47 | 0.007 | 0.075 | ||
| HWC > OB | ||||||||||
| OFC | R | 17 | 23 | 21 | −12 | 3.14 | 0.001 | 0.164 | ||
1
Coordinates are presented in Talairach space
2
Voxel-wise Z-score significance level p<0.05 uncorrected for multiple comparisons within a hypothesized ROI; ROIs listed represent regions of significantly activated clusters within the a priori hypothesized ROI
3
FWE rate (family-wise error rate) used for SVC (small volume correction): Voxel-level significance level (FWE-corrected within the search volume of interest)