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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Invest Dermatol. 2011 Oct 27;132(3 0 1):695–702. doi: 10.1038/jid.2011.329

Figure 5. Topical catalase supplementation inhibits acute UVB-induced Gr-1+CD11b+ myeloid cell skin infiltration in male mice.

Figure 5

Confocal immunofluorescence microscopy was used to quantify mean percentage of colocalized Gr-1/CD11b (green/red) area per 10X field in skin tissue sections. a, Compared to non-irradiated control mice, Gr-1/CD11b colocalization analysis demonstrated UVB-induced Gr-1+CD11b+ myeloid cell skin infiltration in female mice (p=0.0826). Topical catalase treatment had little effect in females. b, Male mice demonstrated UVB-induced Gr-1+CD11b+ myeloid cell skin infiltration (p=0.0018). Compared to UVB exposure and subsequent topical vehicle control treatment, catalase treatment significantly inhibited Gr-1+CD11b+ myeloid cell skin infiltration in male mice (p=0.0019). Horizontal bars represent means.