Table 1.

Patient demographics and clinical assessment

	Mother (N=51)	Grandmother (N=48)	Grandfather (N=35)
Age at RRNL Enrollment, Mean (SD)	32.8 (5.5)	63.2 (7.5)	66.5 (8.5)
Race/ethnicity
Caucasian	47 (92%)	44 (92%)	33 (94%)
Black	3 (6%)	3 (6%)	1 (3%)
Hispanic	1 (2%)	1 (2%)	1 (3%)
Asian	0 (0%)	0 (0%)	0 (0%)
Other/NA	0 (0%)	0 (0%)	0 (0%)
Affected NL child
Cardiac-NL	42 (82%)	39 (81%)	30 (86%)
Rash-NL	9 (18%)	9 (19%)	5 (14%)
Clinical Assessment
Asym/UAS	23 (45%)	44 (92%)	33 (94%)
SS	14 (27%)	1 (2%)	0 (0%)
SLE	7 (14%)	1 (2%)	1 (3%)
SS/SLE	7 (14%)	0 (0%)	1 (3%)
Other	0 (0%)	2 (4%)*	0 (0%)

^*1 GM with ankylosing spondylitis; 1 GM with rheumatoid arthritis

SD = standard deviation

Asym = asymptomatic

UAS = undifferentiated autoimmune syndrome

SS = Sjogren's syndrome

SLE = systemic lupus erythematosus