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Frequency of risk alleles in families with neonatal lupus
| Risk Allele (%) | Comparison with Mother (P-value) | |
|---|---|---|
| TNFα at rs1800629 (risk allele A) | ||
| Mothers (Proband) (n=41) | 38 | - |
| Maternal grandmother (n=38) | 21 | 0.02 |
| Maternal grandfather (n=29) | 32 | 0.59 |
|
| ||
| C6orf10 at rs7775397 (risk allele G) | ||
| Mothers (Proband) (n=41) | 32 | - |
| Maternal grandmother (n=36) | 12 | 0.0065 |
| Maternal grandfather (n=32) | 23 | 0.35 |
