Table 1.
Literature reports of clinical and radiographic findings in bisphosphonate-associated fractures
| Study | Sex (F:M) | Age (years)* | Number of impending/completed fractures | Patients with prodromal pain | Duration of bisphosphonate use (years)* | Fractures with transverse line before fracture | Fractures with lateral cortical thickening | Number of prophylactic reconstruction nails that failed/total number treated with nail | Patients with bilateral fractures |
|---|---|---|---|---|---|---|---|---|---|
| Banffy et al. [2] | 34 F | All > 50 | 12/28 | 6.4 (3–10) | 100% | 100% | 0/6 | 0% | |
| Capeci and Tejwani [4] | 7 F | 61 (53–75) | 7 (impending) | 57.10% | 8.6 (5–13) | 100% | 0/3 | 100% | |
| Koh et al. [9] | 16 F | Median 68 (53–92) | 12/4 | 100% (of completed fractures) | 4.5 (2–7) | 100% | 100% | ||
| Kwek et al. [10] | 17 F | 66 (53–82) | 17 (completed) | 76% | 4.8 (2–8) | 100% | 100% | 53% | |
| Neviaser et al. [11] | 25 F | 69.4 | 25 (completed) | 6.2 (1–10) | 76% | 76% | |||
| Current study | 15:1 | 69.1 (51–90) | 14/10 | 100% | 6.3 (3–10) | 50% (2/4) | 96% (22/23) | 0/14 | 50% |
* Values are expressed as mean, with range in parentheses; F = female; M = male.