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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2011 Sep 29;18(5):739–746. doi: 10.1016/j.bbmt.2011.09.008

Table 3.

Multivariate analysis of clinical outcomes by HistoCheck DSS score quartile groups and treated as a continuous variable

Outcome Group 1
DSS 1.04 – 2.84a
Group 2
DSS >2.84 – 13.75
RR (95% CI)
Group 3
DSS >13.75 – 19.39
RR (95% CI)
Group 4
DSS >19.39 – 36.62
RR (95% CI)
Overall P-value DSS
Continuous P-value
Acute GVHD II-IV 1.00 1.06 (0.79 – 1.41) 1.05 (0.79 – 1.39) 1.16 (0.88 – 1.54) 0.78 0.50
Chronic GVHD 1.00 0.86 (0.61 – 1.21) 0.82 (0.59 – 1.14) 0.97 (0.69 – 1.37) 0.61 0.89
Treatment-related mortality 1.00 1.22 (0.91 – 1.63) 1.13 (0.84 – 1.51) 1.32 (0.98 – 1.77) 0.29 0.58
Relapse 1.00 1.47 (0.93 – 2.32) 0.99 (0.61 – 1.60) 1.44 (0.93 – 2.26) 0.14 0.34
Overall survival 1.00 1.25 (0.98 – 1.61) 1.07 (0.83 – 1.38) 1.28 (1.00 – 1.64) 0.14 0.57
Disease-free survival 1.00 1.30 (1.01 – 1.66) 1.11 (0.86 – 1.42) 1.35 (1.05 – 1.73) 0.06 0.45
Neutrophil engraftmentb 1.00 0.85 (0.41 – 1.75) 0.63 (0.32 – 1.25) 0.48 (0.25 – 0.95) 0.13 0.03
a

Reference group

b

Data reported as an odds ratio in favor of engraftment