Table 2. Serum liver tests and hemodynamic parameters in the patients with non-alcoholic fatty liver disease receiving N-acetylcysteine measured in one-month intervals as mean (SD).
T0 | T1 | T2 | T3 | P | |
ALTb (units/L) | 77.0(26.6) | 78.3(49.3) | 49.2(21.1) | 51.7(17.9) | 0.014 |
ASTa (units/L) | 53.3(34.1) | 48.3(20.2) | 37.6(11.9) | 37.7(10.1) | 0.162 |
ALPc (units/L) | 187.1(50.6) | 185.6(36.3) | 181.8(40.1) | 185.5(50.2) | 0.970 |
Liver hemodynamic parameters | |||||
Liver Span (mm) | 156.5(33.3) | 161.3(35.6) | 164.8(29.3) | 157.5(32.3) | 0.367 |
Spleen Span (mm) | 121.3(16.5) | 121.2(15.3) | 115.3(16.1) | 116.2(16.5) | 0.018 |
Portal vein diameter (mm) | 9.3(1.4) | 9.6(2.0) | 9.5(1.8) | 10.0(1.5) | 0.624 |
Grade of liver steatosis | |||||
Normal | 0 | 1(6.7) | 1(6.7) | 1(6.7) | 0.207 |
Grade 1 | 10(66.7) | 10(66.7) | 11(73.3) | 12(80.0) | |
Grade 2 | 5(33.3) | 4(26.7) | 3(20.0) | 2(13.3) |
a AST:Aspartate transaminase.
b ALT:Alanine transaminase.
c ALP:Alkaline phosphatase.