Figure 3. CNS2 was required for ROR-regulated Th17 cell differentiation.
a, WT and CNS2-deficient T cells cultured under Th0 and Th17 conditions were infected with retroviruses RORα-hCD2, RORγt-hCD2 or empty-hCD2 on day 1, and analyzed on day 4 (gated on hCD2+ cells). b, Statistics of the intracellular staining data from three independent retroviral assays. The percentage values from CNS2-deficient cells were set as 1 for comparison between biological replicates.