Table 1.
Attachment of NGO variants to human FT explant epithelium. FT explants were infected with Pil−Opa− NGO (n = 7) and Pil+Opa−(n = 6), and 16 fields were examined for each explant at each time point. In each field, gonococci were counted within a continuous epithelial strip of at least 150 cells. The data are presented as the mean and SEM of the number of gonococci observed, attached, or internalized. *denotes a significantly (P < 0.05) higher number of attached Pil+Opa− NGO compared to the Pil−Opa− variant at 3 h.
Time (h) | Attached | |
---|---|---|
Pil−Opa− | Pil+Opa− | |
3 | 2.6 ± 0.6 | 7.6 ± 2.6* |
6 | 4.1 ± 1.1 | 6.3 ± 1.4 |
12 | 4.2 ± 1.1 | 5.8 ± 1.3 |
24 | 6.8 ± 0.9 | 6.8 ± 2.0 |
| ||
Internalised | ||
Pil−Opa− | Pil+Opa− | |
| ||
3 | 12.4 ± 1.6 | 18.0 ± 3.4 |
6 | 14.4 ± 1.9 | 16.8 ± 2.4 |
12 | 14.1 ± 1.8 | 15.0 ± 2.4 |
24 | 25.1 ± 1.9 | 18.3 ± 3.9 |