Table 2.
Effect of cranberry NDM on preformed S. gordonii biofilm.
| NDM concentration (μg/mL) | Metabolic activity | Biofilm mass |
|---|---|---|
| 0 (control) | 2.21 ± 0.3 | 2.36 ± 0.41 |
| 2.5 | 2.14 ± 0.18 | 2.33 ± 0.33 |
| 5.0 | 2.24 ± 0.22 | 2.39 ± 0.27 |
| 7.5 | 2.06 ± 0.4 | 2.35 ± 0.44 |
| 10 | 1.96 ± 0.33 | 2.41 ± 0.31 |
| 20 | 1.84 ± 0.59 | 2.34 ± 0.41 |
| 25 | 1.97 ± 1.1 | 2.36 ± 0.29 |
| 50 | 1.86 ± 0.69 | 2.39 ± 0.3 |
| 100 | 1.08 ± 0.44 | 2.35 ± 0.28 |
Bacterial biofilm prepared as described previously was treated with varying concentrations of NDM (2.5 μg/mL to 100 μg/mL) for 60 minutes and 4 hours. The metabolic activity was determined by XTT assay and the biofilm mass determined by the crystal violet staining.