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Effects of MIF inhibition on rat PASMCs proliferation under hypoxia exposure. PASMCs proliferation was measured by MTT (a) and direct cell counting (b). Hypoxia-induced PASMCs proliferation was inhibited by different concentrations of MIF antagonist ISO-1 (10, 50, 100 μM). n = 6. *P < 0.05 versus normoxic control; # P < 0.05 versus vehicle-treated hypoxia group.
