Table 1.
Haemodynamic variables and right ventricle hypertrophy index.
Group | n | RVSP (mmHg) | RV/(LV+S) |
---|---|---|---|
Control | 8 | 23 ± 0.5 | 0.26 ± 0.02 |
Hypoxia | 10 | 48 ± 2.8* | 0.41 ± 0.05* |
Rats were housed intermittently in a hypobaric hypoxia chamber containing 10% oxygen and exposed to these conditions for 10 h/d continuing 28 days. Right ventricle systolic pressure (RVSP) and the ratios of right ventricle/[left ventricle + septum] (RV/[LV+S]) weight were examined as indicators of pulmonary hypertension. Values are means ± SD. *P < 0.05, compared with the corresponding value in control rats.