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Expression of PSA-NCAM and Doublecortin is depleted in the OB, rostral migratory stream (RMS), DG, and subgranular zone (SGZ) of DNMT1-cKO mice. Survey and detail of frontal sections through the OB (A–H), RMS (I–P), and DG (Q–X) stained with bright-field immunohistochemistry for PSA-NCAM (left panel) and Doublecortin (right panel). PSA-NCAM and Doublecortin labeled cells are rare in DNMT1-cKO mice as compared to age matched controls. Scale bars: D,I,T = 10 mm; H,P,X = 1.25 mm.
