Table 3. The T1D disease duration and the anti-IA-2 association of the HLA genes.
| Allele | Anti- IA-2 (−) with T1D duration ≤ 10 years vs. >10 years OR (95% CI) |
Anti- IA-2 (+) vs. Anti- IA-2 (−) with T1D duration ≤10 years OR (95% CI) |
Anti- IA-2 (+) vs. Anti- IA-2 (−) with T1D duration >10 years OR (95% CI) |
|---|---|---|---|
|
HLA-
DQB1*0201 |
0.98 (0.77, 1.24) | 0.67 (0.55, 0.82) | 0.65 (0.53, 0.81) |
| HLA-DRB1*0401 | 0.81 (0.57, 1.15) | 1.94 (1.44, 2.60) | 1.57 (1.15, 2.14) |
| HLA-DRB1*03 | 0.96 (0.73, 1.27) | 0.65 (0.51, 0.82) | 0.62 (0.48, 0.80) |
|
HLA-
DQA1*0501 |
1.03 (0.81, 1.29) | 0.70 (0.58, 0.86) | 0.72 (0.58, 0.89) |
| HLA-A*24 | 1.06 (0.71, 1.58) | 0.53 (0.37, 0.77) | 0.57 (0.40, 0.80) |