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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Ann Neurol. 2012 Jan;71(1):93–109. doi: 10.1002/ana.22627

Figure 5.

Figure 5

The total population of oligodendrocyte lineage cells is increased in WMI. (A, B) Typical distribution of Olig2-labeled nuclei (black; arrowheads) and GFAP-labeled astrocytes (purple; arrows) in controls (A) and WMI cases (B). Insets provide higher power detail of the difference in morphology between Olig2 and GFAP staining. See also Supplemental Fig. 5A. (C) Olig2-labeled nuclei were significantly elevated in WMI cases (lesion and peri-lesion) relative to control (see text and Table S·21 for results of statistical analysis). (D) Olig2 and GFAP were significantly associated (p<0·005) when analyzed across the retrospective cohort of control and WMI cases (Table 1). Dashed lines are the 95% confidence intervals for the group analysis. Scale bars: A, B and insets for A, B, 25 µm.