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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Ann Neurol. 2012 Jan;71(1):93–109. doi: 10.1002/ana.22627

Figure 7.

Figure 7

Expansion of the preOL pool coincides with failure of OL maturation in WMI.

(A) An analysis of preOL density from the prospectivelly collected cases (table 2) found a significant elevation in WMI lesions relative to controls (*p<0·0001). (B) Analysis of the same cohort as in A found no significant difference in OL density in WMI cases vs. controls (p=0·14). (C) The percentage of OLs was significantly reduced in WMI cases vs. controls (*p=0·0006). (D) PreOL density and GFAP were significantly associated (p=0·002) when analyzed across the entire cohort of control and WMI cases. Dashed lines are the 95% confidence intervals for the group analysis.