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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Ann Neurol. 2012 Jan;71(1):93–109. doi: 10.1002/ana.22627

Table 2.

Summary of Clinical and Neuropathological Data for 19 Prospectively Collected Cases

Case Primary
Diagnosis
PCA ST PMI Sex Clinical Diagnosis, Cause of Death Other Neuropathological Diagnosis
1 WMI 29 <1 40 M HF-NI, Hypoplastic right heart None
2 WMI 292/7 22/7 12 M Biventricular cardiac hypertrophy GMH, mild neuronal injury in hippocampus and deep cerebellar nuclei
3 WMI 31 <1 12 M HF-NI, respiratory failure None
4 WMI 32 4 18 M Pulmonary atresia, cardiac arrest Subicular neuronal injury
5 WMI 33 <1 12 M VSD, multi-cystic kidney, NEC, sepsis None
6 WMI 33 84/7 20 M Post-hemorrhagic hydrocephalus, pneumonia GMH, grade IV IVH, neuronal loss/gliosis in hippocampus
7 WMI 331/2 <1 18 F Diaphragmatic hernia, respiratory failure Grade 2 IVH
8 WMI 34 6/7 49 M Polycythemia, recipient twin-twin transfusion syndrome, pericardial effusion None
9 WMI 34 9 40 M Peritonitis, cholestasis Large rightchronic hemispheric hemorrhagic infarct, bilateral cerebellar infarcts, diffuse hippocampal and brainstem neuron loss
10 WMI 37 1 18 M Diaphragmatic hernia, respiratory failure None
11 WMI 401/2 <1 20 M Hypoplastic right heart, cardio-respiratory failure None
12 WMI 45 3 18 F Aortic coarctation, VSD Hippocampal neuronal injury
13 Control 285/7 41/7 26 M NEC Small focal GMH
14 Control 29 4 14 M NEC, intestinal perforation, sepsis Small GMH
15 Control 29 4 16 F Endocarditis Grade 2 IVH
16 Control 294/7 2 22 M Oligohydramnios, IUGR GMH with intraventricular extension
17 Control 31 1 12 M Perforated ileum, respiratory failure None
18 Control 33 15/7 20 F Monozygotic twin, IUGR, renal hypoplasia Mild hippocampalneuronal injury
19 Control 37 2 21 F Diaphragmatic hernia and hypoplastic lung None