Table 3.
KEGG Biochemical Pathway Mappings for S. Stercoralis Clusters
| Clusters per library
|
|||||
|---|---|---|---|---|---|
| KEGG categories representeda | Clusters | L1 | L3i | L1/L3i | Enzymes |
| 1.1 Glycolysis/Gluconeogenesis | 21 | 14 | 6 | 1 | 13 |
| 1.2 Citrate cycle (TCA cycle) | 19 | 13 | 2 | 4 | 8 |
| 1.3 Pentose phosphate cycle | 14 | 10 | 3 | 1 | 9 |
| 1.4 Pentose and glucuronate interconversions | 2 | 2 | 0 | 0 | 2 |
| 1.5 Fructose and mannose metabolism | 15 | 10 | 5 | 0 | 9 |
| 1.6 Galactose metabolism | 7 | 5 | 2 | 0 | 5 |
| 1.7 Ascorbate and aldarate metabolism | 3 | 1 | 2 | 0 | 2 |
| 1.8 Pyruvate metabolism | 24 | 12 | 7 | 5 | 12 |
| 1.9 Glyoxylate and dicarboxylate metabolism | 10 | 7 | 1 | 2 | 5 |
| 1.10 Propanoate metabolism | 14 | 7 | 7 | 0 | 8 |
| 1.11 Butanoate metabolism | 15 | 7 | 8 | 0 | 11 |
| 2.1 Oxidative phosphorylation | 22 | 10 | 5 | 7 | 4 |
| 2.5 Methane metabolism | 1 | 1 | 0 | 0 | 1 |
| 3.1 Fatty acid biosynthesis (path 1) | 8 | 6 | 1 | 1 | 2 |
| 3.2 Fatty acid biosynthesis (path 2) | 5 | 2 | 2 | 1 | 2 |
| 3.3 Fatty acid metabolism | 18 | 7 | 7 | 4 | 6 |
| 3.4 Synthesis and degradation of ketone bodies | 1 | 0 | 1 | 0 | 1 |
| 3.5 Sterol biosynthesis | 3 | 2 | 1 | 0 | 2 |
| 3.6 Bile acid biosynthesis | 9 | 5 | 3 | 1 | 6 |
| 3.8 Androgen and estrogen metabolism | 7 | 3 | 3 | 1 | 4 |
| 4.1 Purine metabolism | 20 | 4 | 12 | 4 | 12 |
| 4.2 Pyrimidine metabolism | 19 | 4 | 12 | 3 | 11 |
| 4.3 Nucleotide sugars metabolism | 5 | 5 | 0 | 0 | 4 |
| 5.1 Glutamate metabolism | 17 | 7 | 7 | 3 | 10 |
| 5.2 Alanine and aspartate metabolism | 17 | 8 | 7 | 2 | 8 |
| 5.3 Glycine, serine and threonine metabolism | 14 | 7 | 6 | 1 | 9 |
| 5.4 Methionine metabolism | 3 | 3 | 0 | 0 | 3 |
| 5.5 Cysteine metabolism | 5 | 3 | 2 | 0 | 4 |
| 5.6 Valine, leucine and isoleucine degradation | 11 | 4 | 6 | 1 | 6 |
| 5.7 Valine, leucine and isoleucine biosynthesis | 5 | 4 | 1 | 0 | 4 |
| 5.8 Lysine biosynthesis | 1 | 0 | 1 | 0 | 1 |
| 5.9 Lysine degradation | 14 | 4 | 10 | 0 | 7 |
| 5.10 Arginine and proline metabolism | 16 | 9 | 7 | 0 | 8 |
| 5.11 Histidine metabolism | 7 | 2 | 5 | 0 | 3 |
| 5.12 Tyrosine metabolism | 15 | 6 | 8 | 1 | 10 |
| 5.13 Phenylalanine metabolism | 11 | 6 | 3 | 2 | 8 |
| 5.14 Tryptophan metabolism | 18 | 6 | 10 | 2 | 7 |
| 5.15 Phenylalanine/tyrosine/tryptophan biosynthesis | 9 | 4 | 5 | 0 | 6 |
| 5.16 Urea cycle and metabolism of amino groups | 4 | 3 | 0 | 1 | 2 |
| 6.1 β-Alanine metabolism | 11 | 7 | 4 | 0 | 6 |
| 6.2 Taurine and hypotaurine metabolism | 4 | 2 | 2 | 0 | 3 |
| 6.3 Aminophosphonate metabolism | 5 | 2 | 2 | 1 | 2 |
| 6.4 Selenoamino acid metabolism | 4 | 4 | 0 | 0 | 4 |
| 6.5 Gyanoamino acid metabolism | 2 | 1 | 1 | 0 | 2 |
| 6.6 D-Glutamine and D-glutamate metabolism | 3 | 2 | 0 | 1 | 2 |
| 6.7 D-Arginine and D-ornithine metabolism | 1 | 0 | 1 | 0 | 1 |
| 6.9 Glutathione metabolism | 6 | 2 | 2 | 2 | 4 |
| 7.1 Starch and sucrose metabolism | 15 | 10 | 3 | 2 | 9 |
| 7.2 Glycoprotein biosynthesis | 5 | 3 | 1 | 1 | 4 |
| 7.4 Aminosugars metabolism | 4 | 2 | 2 | 0 | 3 |
| 8.1 Glycerolipid metabolism | 19 | 8 | 9 | 2 | 14 |
| 8.2 Inositol phosphate metabolism | 4 | 1 | 2 | 1 | 4 |
| 8.4 Phospholipid degradation | 2 | 1 | 1 | 0 | 2 |
| 8.5 Sphingoglycolipid metabolism | 4 | 1 | 2 | 1 | 3 |
| 8.8 Prostaglandin and leukotriene metabolism | 2 | 1 | 1 | 0 | 2 |
| 9.2 Riboflavin metabolism | 1 | 0 | 1 | 0 | 1 |
| 9.3 Vitamin B6 metabolism | 1 | 1 | 0 | 0 | 1 |
| 9.4 Nicotinate and nicotinamide metabolism | 2 | 0 | 2 | 0 | 2 |
| 9.5 Pantothenate and CoA biosynthesis | 5 | 2 | 3 | 0 | 4 |
| 9.8 One carbon pool by folate | 1 | 1 | 0 | 0 | 1 |
| 9.11 Ubiquinone biosynthesis | 25 | 7 | 15 | 3 | 3 |
a
555 total and 312 unique mappings; 61 metabolic pathways are represented out of 83 possible