FIGURE 4.

Set2(1–261) shows unique genetic interactions with transcription mutants. A, growth of bur2Δ/set2Δ or bur2Δ/set2Δ/rco1Δ strains harboring Set2 truncation plasmids plated on media to select for (−URA) or against (+FOA) a plasmid carrying a wild-type copy of BUR2 (pBUR2). B, genetic interactions between set2 mutants and a subset of the yeast deletion mutant collection. Blue color denotes combined sickness in the double mutant where yellow denotes better than expected growth (40). B, representative spores grown on YPD from the dissection of genetic crosses between swr1Δ and set2 mutant strains (PD, parental ditype; NPD, nonparental ditype; T, tetratype).