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. 2011 Dec 9;287(5):3326–3336. doi: 10.1074/jbc.M111.321737

TABLE 1.

Orthologous proteins and identified function

Organism Protein I, P, Ga E valuea Enzyme target Role in pathogenesis
%
C. jejuni EptC 100, 100, 0 0.0 Lipid A, FlgG (7) CAMP resistance, motility (7)
H. pylori Hp0022 33, 50, 11 1e-63 Lipid A (16) Unknown
N. meningitidis Lpt3 29, 43, 29 1.4 LOS core (3-HepII) (14) Bactericidal resistance (14)
Lpt6 29, 43, 29 1.4 LOS core (6-HepII) (15) Unknown
PptA 23, 41, 19 2e-12 PilE (17) Antigenic variation (19), Dissemination of bacteria (18)
E. coli EptB 25, 49, 14 5e-38 LPS core (Kdo) (10) Unknown
S. enterica PmrC 40, 58, 7 1e-101 Lipid A (12) CAMP resistance (12)
CptA 25, 42, 9 5e-18 LPS core (11) CAMP resistance (11)
V. cholera Vca1102 34, 53, 10 2e-77 Unknown Unknown
P. aeruginosa Pa1972 37, 56, 7 4e-89 Unknown Unknown
Pa3310 39, 58, 6 4e-92 Unknown Unknown
Pa4517 23, 42, 17 7e-24 Unknown Unknown
C. coli Cco0328 76, 86, 1 0.0 Unknown Unknown
C. fetus Cff1723 48, 65, 2 7e-162 Unknown Unknown

a Alignments scores (I, identities; P, positives; G, gaps) and E value for each protein compared with C. jejuni EptC using NCBI BLASTP2.2.25.