TABLE 1.
Organism | Protein | I, P, Ga | E valuea | Enzyme target | Role in pathogenesis |
---|---|---|---|---|---|
% | |||||
C. jejuni | EptC | 100, 100, 0 | 0.0 | Lipid A, FlgG (7) | CAMP resistance, motility (7) |
H. pylori | Hp0022 | 33, 50, 11 | 1e-63 | Lipid A (16) | Unknown |
N. meningitidis | Lpt3 | 29, 43, 29 | 1.4 | LOS core (3-HepII) (14) | Bactericidal resistance (14) |
Lpt6 | 29, 43, 29 | 1.4 | LOS core (6-HepII) (15) | Unknown | |
PptA | 23, 41, 19 | 2e-12 | PilE (17) | Antigenic variation (19), Dissemination of bacteria (18) | |
E. coli | EptB | 25, 49, 14 | 5e-38 | LPS core (Kdo) (10) | Unknown |
S. enterica | PmrC | 40, 58, 7 | 1e-101 | Lipid A (12) | CAMP resistance (12) |
CptA | 25, 42, 9 | 5e-18 | LPS core (11) | CAMP resistance (11) | |
V. cholera | Vca1102 | 34, 53, 10 | 2e-77 | Unknown | Unknown |
P. aeruginosa | Pa1972 | 37, 56, 7 | 4e-89 | Unknown | Unknown |
Pa3310 | 39, 58, 6 | 4e-92 | Unknown | Unknown | |
Pa4517 | 23, 42, 17 | 7e-24 | Unknown | Unknown | |
C. coli | Cco0328 | 76, 86, 1 | 0.0 | Unknown | Unknown |
C. fetus | Cff1723 | 48, 65, 2 | 7e-162 | Unknown | Unknown |
a Alignments scores (I, identities; P, positives; G, gaps) and E value for each protein compared with C. jejuni EptC using NCBI BLASTP2.2.25.