Fig. 3.

Sections from the peripapillary region of a 12-WG fetal eye (optic nerve to the right and out of the field). A: The H&E-stained section shows scattered cells within the developing nerve fiber layer (arrowheads) and a demarcation between the inner and outer neuroblastic layer. B: CD31 was only present in the developing choriocapillaris (arrow indicates the bleached RPE in all panels). C: CD39 staining was observed in scattered cells in the nerve fiber layer (arrowheads) and some in the inner portion of the neuroblastic layer. Staining was also seen in the developing choriocapillaris. D: CD45 labels cells in the nerve fiber layer but the number of cells was less then those stained with CD39. E: CXCR4 was observed within the inner neuroblastic layer and in scattered cells within the nerve fiber layer (arrowhead), similar to those in the H&E (A) and the cells labeled with CD39 (C). F: Ki67 staining was only associated with cells within the outermost portion of the neuroblastic layer of retina and within the choroid. B–F: APase reaction product.