Table 3. Interactions of lipopolysaccharide and adiponectin on involucrin and growth factors.
Target gene | Group | 4 h | 8 h | 24 h |
Involucrin | LPS | 2.91±0.12* | 4.86±0.34* | 1.58±0.24 |
Adipo | 0.87±0.13† | 2.50±0.21* † | 0.97±0.23 | |
LPS + Adipo | 0.89±0.21† | 2.02±0.14* † | 0.69±0.10† | |
TGFβ1 | LPS | 1.06±0.07 | 0.77±0.07 | 0.83±0.19 |
Adipo | 0.28±0.04* † | 1.03±0.06 | 0.52±0.09* | |
LPS + Adipo | 0.96±0.14# | 0.75±0.04* # | 0.84±0.05 | |
KGF | LPS | 0.63±0.16 | 2.01±0.11* | 0.59±0.03* |
Adipo | 0.19±0.04* † | 0.64±0.06* † | 1.02±0.10† | |
LPS + Adipo | 0.49±0.09* | 0.68±0.08† | 0.41±0.05* # |
Effects of lipopolysaccharide (LPS; 2 µg/ml) and/or adiponectin (Adipo; 1 µg/ml) on the mRNA expression of involucrin, TGFβ1, and KGF at 4 h, 8 h, and 24 h expressed as fold of control. Mean ± SEM; n = 6;
p<0.05 different from control,
different from LPS-treated cells,
different from adiponectin-treated cells.