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Escape by Criterion* (Per Protocol Population)
| Criterion | LTG XR | LTG XR |
|---|---|---|
| (300 mg/day) | (250 mg/day) | |
| (n = 93) | (n = 81) | |
| n (%) | n (%) | |
| Total | 25 (27) | 24 (30) |
| 1 — Doubling of monthly seizure frequency | 5 (5) | 13 (16) |
| 2 — Doubling of highest 2-day total | 16 (17) | 17 (21) |
| 3 — New, more severe seizure type | 6 (6) | 3 (4) |
| 4 — Prolongation/worsening of generalized seizures | 3 (3) | 2 (2) |
*Patients may have met more than 1 escape criterion
