Table 2.
Urine/Plasma levels* |
||||
---|---|---|---|---|
Low/Low | Low/High | High/Low | High/High | |
Estrone: luteal urine & luteal plasma | ||||
1.00 (ref) | 0.85 (0.52–1.39) | 0.56 (0.32–0.97) | 0.65 (0.43–0.99) | |
Estradiol: luteal urine & luteal plasma | ||||
1.00 (ref) | 1.19 (0.74–1.90) | 0.63 (0.35–1.13) | 0.67 (0.43–1.05) | |
Estrone: luteal urine & follicular plasma | ||||
1.00 (ref) | 0.97 (0.61–1.53) | 0.68 (0.41–1.14) | 0.64 (0.40–1.04) | |
Estradiol: luteal urine & follicular plasma | ||||
1.00 (ref) | 0.97 (0.61–1.54) | 0.60 (0.36–1.01) | 0.58 (0.34–0.97) |
Multivariate models adjusted for: first morning urine (yes, no), BMI at age 18 (<21, 21–<23, ≥23), age at menarche (<12, 12, 13, ≥14), parity & age at first birth (nulliparous, 1–2 children & <25 yrs, 1–2 children & 25–29 yrs, 1–2 children & ≥30 yrs, ≥3 children & <25 yrs, ≥3 children & ≥25 yrs), family history of breast cancer (yes, no), history of benign breast disease (yes, no)
Cutpoints based on medians of urine and plasma levels