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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Exp Eye Res. 2011 Sep 24;95(1):8–15. doi: 10.1016/j.exer.2011.09.009

Figure 3. Response of bovine corneal endothelial cells to activation of PAR-1 receptors by thrombin.

Figure 3

Panel A: MLC phosphorylation in response to thrombin is inhibited by Y-27632 (Rho kinase inhibitor) and Chelerythrin (a PKC inhibitor). C: Control (Untreated cells). T: Thrombin; NP: Non-phosphorylated; P: Mono-Phosphorylated; PP: Di-phosphorylated; Y: Y-27632; Ch: Chelerythrin. Panel B: Bar graph showing permeability to Horseradish peroxidase (HRP; ~44 kDa). Increase in optical density at 470 nm signifies increase in permeability to HRP. Results summarized from our previous report (Satpathy et al., 2004).