Figure 3.

Immunostaining pattern for sera collected from 76 irritable bowel syndrome patients, 66 of whom had anti-enteric neuronal antibodies in their blood, and 22 controls, 13 of whom had anti-enteric neuronal antibodies in their blood. (A) Examples of immunostaining in the nucleus alone, the cytoplasm alone and in both nucleus and cytoplasm. (B) Immunostaining in the neuronal nuclei predominated relative to staining of the cytoplasm alone or staining of nuclei and cytoplasm. IBS, irritable bowel syndrome.