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. 2012 Jan 16;18(1):78–85. doi: 10.5056/jnm.2012.18.1.78

Table 2.

Results Obtained With Invitrogen, Inc. Immune Response Biomarker Profiling Assay

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IBS, irritable bowel syndrome; IBS-A, serum samples with anti-enteric nueronal antibodies; IBS-B, serum samples without anti-enteric neuronal antibodies.

Three blinded samples known to contain anti-enteric neuronal antibodies in immunostain assays (IBS-A) and 3 samples without antibodies in immunostain assays (IBS-B) were pooled. Out of 8,000 possibilities, 3 antigens were identified as reacting with antibodies in the IBS-A sera. No "hits" were obtained with IBS-B sera. The 3 identified antigens ("hits") in IBS-A sera consisted of a nondescript ribonucleoprotein complex, Anti-Ro 52,000 MW and small nuclear ribonucleoprotein polypeptide A.